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Tatsuo Yamamoto Selected Research

isospaglumic acid (NAAGA)

9/2012NAAG peptidase inhibition in the periaqueductal gray and rostral ventromedial medulla reduces flinching in the formalin model of inflammation.
8/2008Intracerebroventricular administration of N-acetylaspartylglutamate (NAAG) peptidase inhibitors is analgesic in inflammatory pain.
1/2007Local administration of N-acetylaspartylglutamate (NAAG) peptidase inhibitors is analgesic in peripheral pain in rats.
7/2004Antinociceptive effects of N-acetylaspartylglutamate (NAAG) peptidase inhibitors ZJ-11, ZJ-17 and ZJ-43 in the rat formalin test and in the rat neuropathic pain model.

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Tatsuo Yamamoto Research Topics

Disease

26Pain (Aches)
02/2022 - 04/2002
18Periodontitis
01/2021 - 06/2006
15Inflammation (Inflammations)
01/2017 - 09/2002
15Neoplasms (Cancer)
01/2014 - 02/2002
13Infections
01/2021 - 07/2002
11Neuralgia (Stump Neuralgia)
01/2021 - 08/2003
11Pre-Eclampsia (Preeclampsia)
01/2021 - 10/2004
10Hypertension (High Blood Pressure)
01/2021 - 04/2004
8Acute Kidney Injury (Acute Renal Failure)
01/2019 - 04/2004
8Hyperalgesia
06/2015 - 08/2003
8Nephritis
07/2012 - 11/2002
7Fibrosis (Cirrhosis)
03/2014 - 01/2004
6Proteinuria
06/2022 - 09/2004
5Endometriosis
01/2018 - 07/2002
5Choriocarcinoma
09/2016 - 07/2003
5Obesity
06/2016 - 08/2009
5Glomerulonephritis
10/2008 - 11/2002
5Renal Insufficiency (Renal Failure)
10/2008 - 09/2002
4Tooth Loss
01/2020 - 01/2012
4Chronic Renal Insufficiency
01/2019 - 05/2007
4Pneumonia (Pneumonitis)
01/2019 - 01/2012
4Hypoxia (Hypoxemia)
10/2014 - 10/2006
4Carcinogenesis
10/2010 - 02/2003
4Alveolar Bone Loss
11/2009 - 04/2009
4Hemolytic-Uremic Syndrome
10/2003 - 11/2002
3Alzheimer Disease (Alzheimer's Disease)
11/2022 - 01/2020
3Hemorrhage
01/2021 - 04/2009
3Type 2 Diabetes Mellitus (MODY)
04/2020 - 01/2009
3Postoperative Pain
01/2020 - 01/2005
3Periodontal Diseases (Periodontal Disease)
01/2019 - 03/2004
3Bone Neoplasms (Bone Cancer)
01/2017 - 01/2005
3Nephrotic Syndrome (Syndrome, Nephrotic)
11/2015 - 09/2003
3Thrombocytopenia (Thrombopenia)
10/2013 - 07/2002
3Pregnancy-Induced Hypertension (Hypertension, Pregnancy Induced)
07/2013 - 02/2008
3Neoplasm Metastasis (Metastasis)
07/2008 - 02/2002
3Carcinoma (Carcinomatosis)
07/2008 - 07/2004
3Cardiovascular Diseases (Cardiovascular Disease)
02/2008 - 05/2004

Drug/Important Bio-Agent (IBA)

17Analgesics (Analgesic Drugs)IBA
02/2022 - 04/2002
14Messenger RNA (mRNA)IBA
01/2021 - 05/2000
13Formaldehyde (Formol)FDA Link
02/2022 - 09/2002
12Proteins (Proteins, Gene)FDA Link
06/2022 - 02/2002
10Pharmaceutical PreparationsIBA
01/2021 - 01/2005
7CytokinesIBA
08/2015 - 11/2002
78-Hydroxy-2'-DeoxyguanosineIBA
10/2011 - 10/2007
6Indicators and Reagents (Reagents)IBA
01/2019 - 03/2004
6EnzymesIBA
01/2017 - 01/2005
6Peptides (Polypeptides)IBA
10/2015 - 01/2007
6Morphine (MS Contin)FDA LinkGeneric
06/2015 - 03/2004
6CollagenIBA
01/2015 - 02/2006
6SaltsIBA
07/2012 - 02/2004
6Transforming Growth Factor beta (TGF-beta)IBA
10/2010 - 11/2002
6Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
04/2010 - 08/2005
5CreatinineIBA
06/2022 - 09/2003
5Acetaminophen (Paracetamol)FDA LinkGeneric
02/2022 - 01/2005
5SteroidsIBA
11/2015 - 07/2002
5Panton-Valentine leukocidinIBA
10/2015 - 08/2006
5CarrageenanIBA
06/2015 - 11/2003
5Glutamate Carboxypeptidase II (N-Acetylaspartylglutamate Peptidase)IBA
09/2012 - 07/2004
5LipopolysaccharidesIBA
10/2011 - 10/2007
5Angiotensin IIIBA
01/2011 - 05/2007
5Reactive Oxygen Species (Oxygen Radicals)IBA
03/2010 - 10/2007
5Prednisolone (Predate)FDA LinkGeneric
01/2006 - 03/2003
4C-Reactive ProteinIBA
10/2019 - 09/2002
4Opioid Analgesics (Opioids)IBA
06/2015 - 01/2005
4Staphylococcal enterotoxin FIBA
01/2015 - 03/2005
4Cisplatin (Platino)FDA LinkGeneric
01/2014 - 10/2004
4isospaglumic acid (NAAGA)IBA
09/2012 - 07/2004
4Lysine (L-Lysine)FDA Link
10/2011 - 12/2008
4Peptide Hydrolases (Proteases)FDA Link
10/2011 - 10/2007
4OrexinsIBA
01/2007 - 09/2002
3ORALIT (ORS)IBA
01/2021 - 06/2016
3Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2021 - 01/2019
3AlbuminsIBA
04/2020 - 01/2009
3TeaIBA
01/2020 - 01/2011
3Immunoglobulin G (IgG)IBA
01/2019 - 02/2002
3Cyclophosphamide (Cytoxan)FDA LinkGeneric
11/2015 - 04/2003
3Rocuronium (Zemuron)FDA LinkGeneric
10/2015 - 03/2013
3Hydroxyl RadicalIBA
08/2015 - 10/2006
3salicylhydroxamic acid (SHAM)IBA
03/2014 - 06/2004
3Gefitinib (Iressa)FDA Link
01/2014 - 06/2006
3ReninIBA
07/2012 - 01/2005
3Leukocidins (Leukocidin)IBA
04/2011 - 04/2010
33-nitrotyrosineIBA
01/2011 - 05/2009
3UbiquitinIBA
10/2010 - 10/2003
3LipidsIBA
03/2010 - 09/2002
3Glutathione Disulfide (GSSG)FDA LinkGeneric
11/2009 - 12/2008
3Oxygen (Dioxygen)IBA
11/2009 - 06/2009
3Ascorbic Acid (Vitamin C)FDA LinkGeneric
05/2009 - 11/2007
3AngiotensinogenIBA
11/2008 - 05/2007
3N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
09/2008 - 01/2005
3KetamineFDA LinkGeneric
09/2008 - 01/2005
3Biomarkers (Surrogate Marker)IBA
09/2008 - 03/2006
3CholesterolIBA
11/2007 - 09/2002

Therapy/Procedure

18Therapeutics
12/2020 - 07/2002
10Ligation
06/2011 - 08/2003
6Spinal Injections
01/2017 - 09/2002
6Analgesia
06/2015 - 03/2004
6Drug Therapy (Chemotherapy)
10/2010 - 02/2002
4Toothbrushing
12/2013 - 09/2002
4Renal Dialysis (Hemodialysis)
04/2004 - 05/2000